Boala Whipple

Boala Whipple

Lipodistrofia intestinala Whipple

Cauza rara de malabsorbtie, probabil dato­rata unei infectii bacteriene cu Tropheryma whippelii.

Se caracterizeaza prin simptome digestive debutate gradual (scadere in greu­tate, diaree, steatoree, hemoragie gastro-in­testinala, durere abdominala), limfadenopa­tie, dureri articulare, tulburari psihice (pier­deri de memorie). Poate asocia hiperpig­mentare difuza aparuta mai ales la barbatii de varsta mijlocie.

Evolueaza fatal, fara antibioterapie.

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Despre: Boala Whipple, lipodistrofia intestinala, malabsorbtie